27 November

09:30 – Registration

10:00 – Welcome & Introduction

Claude Leclerc and Salem Chouaib (Organizing Committee)

Norbert Ifrah (Institut national du cancer, Boulogne-Billancourt)
Christine Chomienne (Aviesan’s Cancer Institute, Paris & Institut national du cancer, Boulogne-Billancourt)

10:30 – Keynote lecture : Giorgio Trinchieri (NIH-NCI, Bethesda)

Inflammation and tumor microenvironment

Chairmen : Jean-Yves Blay (Centre Léon Bérard, Lyon) and Alexander Eggermont (Gustave Roussy, Villejuif)

11:15 – Session 1 : Immune checkpoints and costimulatory molecules

Chairmen : Eric Vivier (CIML, Marseille) and Salem Chouaib (Gustave Roussy, Villejuif)

Melanoma serves as the model for solid tumors
Alexander Eggermont (Gustave Roussy, Villejuif)

Is there a place for ICI in the context of oncogenic addiction?
Jacques Cadranel (Hôpital Tenon, Paris)

Immunotherapy in kidney cancer: current situation and challenges
Bernard Escudier (Gustave Roussy, Villejuif)

12:45 – Lunch

14:15 – Introduction

Yves Levy (Aviesan, Paris)

14:30 – Session 2 : Tumor microenvironment

Chairwoman/man : Catherine Sautès-Fridman (Centre de recherche des Cordeliers, Paris) and Vassili Soumelis (Institut Curie, Paris)

Hypoxia-inducible factors endow cancer cells with the capacity for tumor initiation and immune evasion
Gregg Semenza (John Hopkins University, Baltimore)

Combating immunosuppression in the tumor microenvironment
Benoit van den Eynde (Ludwig Institute for Cancer Research, Brussel)

Defining molecular identity of intratumoral T cells to design better cancer immunotherapies
Sergio Abrignani (INGM, Milan)

Chemotherapy and anti-cancer immune response: how to use cytotoxic agent to improve efficacy of immune-oncologic drugs?
François Ghiringhelli (Centre de Recherche Inserm-LNC, Dijon)

16:30 – Coffee Break

17:00 – Session 3 : Novel approaches to analyze tumor microenvironment

Chairmen: Daniel Olive (CRCM, Marseille) and Pierre Saintigny (CRCL, Lyon)

PD-L1 and associated biomarkers: What’s new and what’s next?
Janis Marie Taube (John Hopkins University, Baltimore)

Immune contexture and immunoscore in the era of cancer immunotherapy
Jérome Galon (Centre de recherche des Cordeliers, Paris)

18:00 – End of the first day